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Section: Testing > Safety/Stability

While the company stands by its science, it is ending the global sales of baby powder containing mineral starch and switching to a formula based on corn starch,

$18.8 M Payout in J&J Talc Lawsuit Could Upset Settlement Offer

The ruling could sway individuals in the tens of thousands of other cases to also pursue claims in front of a jury, pressuring the judge overseeing the settlement case.

The bigger impact is that concerns over the potential endocrine-disrupting effects of bisphenols will no doubt put other cosmetic ingredients with the same alleged effects front and center (again), drawing interest from regulators.

Endocrine Disruptors in the EU, SCCS Opinions and NGO Pressure to Crack Down

From November 2022–February 2023, organizations in seven European Union member states tested 121 products and found bisphenols of high concern in 47 of them, per Chemical Watch. NGOs are urging regulators to impose stricter regulation on all bisphenols.

RIFM has submitted Safety Assessments covering approximately 200 materials for peer review, totaling 1,700 now or soon to be available.

RIFM Publishes Assessment of 1,500th Fragrance Material Marking Major Milestone

RIFM has submitted Safety Assessments covering approximately 200 materials for peer review, totaling 1,700 now or soon to be available.

The guides are regularly revised to incorporate the progress of scientific knowledge in general and the experience gained particularly in the field of testing and safety evaluation of cosmetic ingredients.

11 Changes to SCCS Guides for Cosmetics Safety Testing — Plus a Note on 'Nano'

The European Union's (EU's) Scientific Committee on Consumer Safety (SCCS) recently updated its notes of guidance (NoG) for cosmetics and cosmetic ingredient safety testing, emphasizing alternatives to animal testing and more.

The FDA reminded consumers to check its blacklist of hand sanitizers they should not use due to methanol content, insufficient active ingredient or false and misleading/unproven claims.

FDA on Hand Sanitizers, Topical Irritation Testing and Biosimilars

Recent FDA activities include education for consumers on hand sanitizers and biosimilars, and guidance for testing the irritation/sensitization potential of topicals in relation to abbreviated new drug applications. Following is a roundup.

While some (if not many) of these allegations may be unfounded or misguided, it underscores the critical role of safety and toxicity testing even under non-typical product use conditions.

Unilever, J&J, Olaplex and L'Oreal Still Treading Legal Waters Over Lilial, Benzene

Olaplex, Redken, OGX, Dove, Nexxus, Suave, Tigi and Tresemmé brands are still making headlines as they tread legal waters over alleged Lilial and benzene content. Following are recent updates.

A letter from the FDA to Valisure, dated Dec. 5, 2022, highlighted 'methodological deficiencies' and 'analytic descrepancies' in the company's testing.

FDA, Unilever and GSK Challenge Valisure's Benzene Findings, Test Methods

The FDA recently raised concerns over the test methods of Valisure, the Connecticut-based lab whose reports over benzene in sunscreen and dry shampoo products from Unilever, GSK and others have prompted recalls and class action suits.

In evaluating how different solvents may affect the rheology of personal care formulas, it is helpful to consider that different formulation types have distinct relationships between viscosity and elasticity depending on the factors generating their elastic properties.

How Natural Butylene Glycol Advances Market and Rheology Dynamics

Demand for sustainable ingredients in cosmetics and personal care is well-known. Here, a sustainable natural butylene glycol is described to advance this trend and its effects on viscosity and elasticity are assessed in five test formulas.

Avon was acquired by Natura Cosmetics SA in 2020 and that year, the company removed talc from its products marketed in the United States — at a time it was defending nearly 130 talc lawsuits.

Avon Takes a $40 M Hit in Talc/Cancer Suit

The plaintiff, 76-year-old Rita Chapman of Scottsdale, Arizona, alleged that the use of Avon's talc-containing products tainted with asbestos caused her mesothelioma.

This follows the company's recall on these products in November 2021; at that time, the company had not received any reports of adverse events following the use of these products.

P&G Pays Out $8 M in Benzene Settlement

The settlement benefits consumers who purchased Secret, Old Spice, Pantene, Waterless, Aussie, Herbal Essences or Hair Food aerosol antiperspirant, deodorant, body spray, dry shampoo or dry conditioner products between Nov. 4, 2015, and Dec. 31, 2021.

Many of the allergens identified were fragrances and other botanicals, according to ScienceAlert, which have become a leading cause of contact dermatitis.

JAMA Letter Cautions: Most 'Natural' Skin Care Contains Allergens

A Research Letter published in JAMA Dermatology highlighted the prevalence of contact allergens in natural skin care in a study of 1,651 products on the U.S. market.

Black women could be disproportionately affected, as 60% of participants who reported using hair straighteners self-identified as Black women.

Study Connects Hair Straightener Use to Incident Uterine Cancer

Hair straightening products could be linked to higher incidences of uterine cancer, a study of nearly 34,000 women in the U.S. recently found.

'...There is currently insufficient relevant and reliable scientific data to conduct realistic ERAs and there is not enough scientific data to support sunscreen ingredient bans,' wrote the Personal Care Products Council (PCPC).

PCPC on NAS Report: 'Not Enough Data to Ban Sunscreens'

The Personal Care Products Council has released a statement responding to the National Academy of Sciences Report, "Review of Fate, Exposure, and Effects of Sunscreens in Aquatic Environments and Implications for Sunscreen Usage and Human Health."

Microbiological test methods for w/o formulas have raised questions in terms of their suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods and options for their optimization. It also critically observes to what extent test results provide relevant information for an appropriate safety assessment. Part II, in August 2022, will explore a holistic approach to more accurately assess microbiological safety.

Determining Preservative Efficacy in W/O Formulas, Part I: Test Performance and Limitations

Microbiological test methods for w/o formulas have raised questions in terms of suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods.

Revisions include adding “special cosmetics” and “cosmetics using new ingredients” to the key categories of sampling testing.

China Revises Cosmetic Sampling Testing Rules, Calls for Comments

The measures will focus on testing in children’s cosmetics, special cosmetics and cosmetics containing new ingredients. Measures are open to public comment through July 14, 2022.

The MyMicrobiome Standard certification for JD Jojoba Oil and JD Lusteris guarantees a microbiome-friendly product for the skin.

Jojoba Desert Ingredients Achieve MyMicrobiome Standard Certification

The MyMicrobiome Standard certification for JD Jojoba Oil and JD Lusteris is said to guarantee a microbiome-friendly product for the skin.

The sensitivity of the test indicates it could be useful as a screening tool and could contribute to research on alternative skin corrosion tests.

Researchers Develop Invertebrate Alternative In vivo Skin Corrosion Test

Work published in Environmental Pollution describes an invertebrate alternative in vivo skin corrosion test that reportedly is more sensitive to acids and alkalis than traditional skin models.

For multifunctional products such as moisturizing hand sanitizers, the sanitizer claim requires a significant reduction (2-3 log) of a microorganism population while the moisturizer claim requires data showing an increase in skin moisture.

Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer

Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.

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