Search Cosmetics & Toiletries: Page 2

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Section: Testing > Safety/Stability

The CTPA and the U.K. cosmetic industry wants to promote the use of new approach methodologies (NAMs) as alternatives to animal testing for these vital safety requirements under other chemicals legislation, especially UK Reach.

CTPA Convenes to Progress the Use and Regulatory Acceptance of Animal Testing Alternatives

The CTPA and the U.K. cosmetic industry wants to promote the use of new approach methodologies (NAMs) as alternatives to animal testing for these vital safety requirements under other chemicals legislation, especially UK Reach.

Animal-Aid has pledged £51k to accelerate research, development and commercialization of acute toxicity tests by ethical safety testing laboratory XCellR8.

Animal Aid Funds XCellR8 for Animal-free Safety Testing

Animal-Aid has pledged £51k to accelerate the research, development and commercialization of acute toxicity tests by ethical safety testing laboratory XCellR8.

Most Rosa centifolia-derived ingredients are reported to function as skin conditioning agents in cosmetic products. Other functions associated with ingredients in this group include abrasives, antioxidants, fragrance ingredients and skin protectants.

CIR Assesses Safety of Rosa Centifolia Derivatives in Cosmetics

The CIR reviewed the safety of Rosa centifolia-derived ingredients, most of which are reported to function as skin conditioning agents in cosmetic products; read on for the findings.

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Hazard List, Harmonization, Toxicity Tests and O'Malley Appointment: ECHA Updates

This ECHA update includes one addition to the hazardous chemicals list, two proposals for harmonized classification/labeling (eugenol and tetrahydrofurfuryl methacrylate), advice for toxicity test dosing and the appointment of Shay O'Malley.

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Analyze, Optimize: Ensuring Pollution Won’t ‘Get Under Your Skin’

Anti-adhesion, removability, anti-penetration and cleansing properties were assessed in steps, as described here, to optimize formulas for effective anti-pollution protection. An approach was designed to test cosmetic ingredients and formulas for their abilities to suppress the negative effects of pollution in skin.

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Letter to Editor Questions Benzophenone Study; Author and Industry Expert Respond

A Letter to the Editor in Chemical Research in Toxicology points to flaws in a study gaining recent attention and calling for the removal of octocrylene-containing sunscreens from the market. The author responds; as does an additional industry expert, David Steinberg.

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Toxicological Evaluation of Cosmetics: A Primer

A cosmetic toxicologist can provide a clear-eyed view of the potential hazards and quantifiable risks of a product based on its composition. This primer briefly explains how.

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Research Reviews Non-penetrating Sunscreen Vehicles, Looks to Jojoba

Several "carriers for the future" were highlighted, such as lipid carriers, cyclodextrin derivatives, encapsulation approaches and non-penetrating sunscreens incorporating UV filters and jojoba oil conjugates.

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SCCS on Methyl Salicylate: Safe Within Cosmetic Limits, Weak Sensitizer

The European Scientific Committee on Consumer Safety (SCCS) recently issued its preliminary Opinion on the safety of methyl salicylate.

BASF and Givaudan collaborated to develop and validate alternative animal testing methods, leading to the first toxicology testing strategy without animals that was adopted by OECD.

BASF and Givaudan Develop First OECD-Approved Animal Test Alternatives

The OECD has, for the first time, approved a non-animal strategy to assess skin sensitization based on three tests. In addition, the Kinetic Direct Peptide Reactivity Assay was approved to predict the intensity of reactions. All tests are the results of BASF/Givaudan joint efforts.

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Cosmetics Study Prompts Legislation to Ban PFAs

The authors concluded: "The cosmetic categories that had the highest percentage of high fluorine products were foundations (63%), eye products (58%), mascaras (47%) and lip products (55%)."

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Confounding Labels: One ‘Natural’ = 100+ ‘Chemicals’

As most formulators are aware, creating a product with three or more botanicals in it means a final formula containing more than 200 chemicals. How is this better for skin? It's not, according to this commentary.

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Mary Kay Blends Retinol with TRPV1 Antagonist for Non-irritating Efficacy

During the 2021 SID virtual meeting, Mary Kay Inc., shared work combining the efficacy of retinol with botanicals to reduce its irritation; the company also announced it will fund four research grants related to skin health.

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Concerns Over Charcoal Safety Raised in Crest Toothpaste Lawsuit

A class action lawsuit filed in New York alleges that P&G promoted the safety of its activated charcoal-containing Crest toothpaste despite expert opinions finding a lack of safety and efficacy substantiation.

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FDA Cautions: Hair-smoothing Products Can Release Formaldehyde

The U.S. Food and Drug Administration recently released a statement warning users of the potential for hair-straightening products to release formaldehyde gas, a known carcinogen, during heat treatments.

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900+ Hand Sanitizer Poisonings, Mexican Imports Put on FDA Alert

CBS News recently reported 900+ Americans were accidentally poisoned by hand sanitizers in January 2021 alone. In relation, the FDA has placed an import alert on all Mexican sanitizers, which have been the source of multiple offenses.

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Methanol Content and How to Test for it: FDA Guidance

The U.S. Food and Drug Administration has outlined a policy for companies to test alcohol (ethanol) or isopropyl alcohol for hazardous methanol content prior to their use in hand sanitizer products.

According to the researchers, it is likely the microplastics entered the mothers' bodies by ingestion or through respiration.

Microplastics Detected in Human Placenta: Industry Implications

A new study published in Environmental International has identified the presence of microplastics in human placenta. While science examines their risk, industry (including cosmetics) might expect to hasten their replacement and removal.

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